A neuropsychiatric condition affecting behavior and motor function, resulting in non-responsiveness while appearing awake. Often associated with Schizophrenia


Treatment and Managegment

  1. Psychopharmacology
    • Benzodiazepines
    • Antidepressants
    • Muscle Relaxants
    • Antipsychotic Medications
  2. Brain Stimulation Therapy: electroconvulsive therapy and NMDA antagonists.

DSM-5

Three of twelve symptoms must be present:

  • Stupor: inability to move or respond to stimuli
  • Catalepsy: rigid body posturing
  • Mutism
  • Waxy Flexibility: body remains in whatever position it is placed.
  • Negativism: lack of verbal response
  • Posturing: holding positions acting against gravity.
  • Mannerisms: extreme or odd mannerisms
  • Stereotypy
  • Agitation without reason
  • Grimacing
  • Echolalia
  • Echopraxia
  • Rigidity and Automatic Obedience